He was one of the few who played in the humiliating game when Gary Neville was in charge of Los Che.
“Messi is as awesome as ever,” he said to reporters on Monday.
“Barcelona are the overwhelming favourites in the league, in the Champions League and in the cup.
“I don’t think we want to go looking for revenge, but it’s a special match because we play again against a powerful team.
“Two years ago it was very unpleasant, one of the toughest days, without a doubt.
“But since then we have had matches against Barcelona in which we have competed.”
Having been comprehensively beaten by Real Madrid, the striker was asked if that will affect Valencia going into the cup game.
“Saturday’s game is over,” he continued.
“I think the result was a bit deceptive, but we have to focus against another great rival.
“We have to go with the idea that it’s not a League match since we have the time at the Estadio Mestalla to confirm our passage to the final.”
Spanish referees have come under scrutiny recently, but Rodrigo doesn’t expect them to negatively affect the tie.
“I don’t think that the referee goes to the game with the intention of favouring anyone,” he noted.
“We trust all the referees and a bad decision can greatly affect our work, but it’s part of the game.”